Picamilon and it's Place in the Group of
Well-Known Nootropic Drugs
[Article in Russian]
Institute of Pharmacology,
8, Baltiyskaya St., Moscow, 125315, USSR
Picamilon - N-nicotinoyl-GABA is a new vasoactive drug with nootropic
properties. It has anti-amnesic activity on two models of amnesia of passive
avoidance response, caused by maximum electro shock and scopolamine on mice.
Picamilon increases exploratory behavior in open field. In comparison with the known nootropic drugs,
picamilon produces a specific antiamnestic effecy in lower doses, than piracetam, etiracetam, aniracetam.
Effects of deanol, aceglumat, centrophenoxine, and picamilon, received in the same doses, are similar. But
picamilon is less potent than nicergoline.